Abstract
Neuroleptic-induced neurological side effects have usually been classified as acute dystonia, Parkinsonism, akathisia and tardive dyskinesia (TD). Recent observations in monkeys and man have revealed that classification in this way is over-simplified because nearly identical extrapyramidal syndromes may appear as a result of 1) neuroleptic treatment, 2) withdrawal of neuroleptic treatment and initiation of anticholinergic treatment, or 3) age and/or the psychotic process. The aim of the present study was to determine the prevalence of the these first two syndromes.Two hundred and two long-term neuroleptically treated psychiatric inpatients were evaluated 1) during treatment with their usual neuroleptic medication, but without anticholinergics for 2 days, and 2) after treatment with anticholinergics for 14 days, the last two of which the neuroleptic treatment was stopped. Patients with extrapyramidal symptoms were divided into subgroups depending on response to this pharmacological manipulation: those who ...
Published Version
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