Kinetics study on the reactive extraction of homophenylalanine enantiomers with BINAP-copper complex

Abstract

ABSTRACTThis paper reports on the kinetics study of the reactive extraction of homophenylalanine (Hph) enantiomers with BINAP (2,2’-Bis(diphenylphosphino)-1,1’-binaphthalene)-copper complex (BINAP-Cu) as the chiral selector. The kinetic model was established based on the theory of interfacial chemical reactive extraction. Simultaneously, the effects of agitation speed, interface area, pH value of the aqueous phase, initial concentration of Hph enantiomers and initial concentration of BINAP-Cu on the specific rate of extraction were investigated. The forward rate constants of the reactions in reactive extraction process were found to be 6.16 × 10−4 m2.5mol−0.5s−1 for D-Hphe and 7.303 × 10−4 m2.5mol−0.5s−1 for L-Hphe.