Abstract
PAH accumulation in renal cortical slices of rats is age-related different. Kinetic parameters were quantified using the Lineweaver-Burk analysis. The Michaelis constant for PAH uptake is 0.50 mM in all age groups, i.e., the affinity of PAH for the transport sites is the same. The maximum PAH concentrations (steady-state) in renal cortical slices from 5-, 20-, 33-, and 55-day-old rats are 0.91, 1.72, 2.57, and 1.72mM, respectively. This finding suggests that the number of transport sites is increasing during the postnatal development of the kidney.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
