Abstract
Abstract The kinetics of oxidation of pyridoxine (PRX) by chloramine-T (CAT) in the presence of hydrochloric acid (0.04–0.14 M) have been studied over the temperature range of 303–323 K. The rate of the reaction shows first-order dependence on each of CAT, PRX, and chloride ion concentrations. The reaction rate is independent of hydrogen ion concentration. Variations of ionic strength and dielectric constant of the medium have negligible effect on the rate. Addition of the reaction product, p-toluenesulfonamide, decreases the rate showing a negative first order dependence. The solvent isotope effect has been studied by using heavy water. The activation parameters, Ea, ΔH\ewq, and ΔS\ewq are computed from the reaction rates at various temperatures. The mechanism of PRX oxidation proposed and the rate law derived are consistent with the observed kinetics.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
