Abstract
Over the decades, reconstituted systems have been exploited for kinetics measurements of biological processes in vitro. However, since in live cells, different biochemical processes are always inter-connected and taking place in a confined geometry, studies of an isolated system can never account for the whole picture. On the other hand, access to kinetics of dynamic processes directly inside the cell has been problematic since the molecules of interest are normally not synchronized with respect to binding state.
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