Abstract
The hydrolysis rate of 1-N-naphthylphthalamic acid (Nap) was measured as a function of pH in the range of 0.9-5 and proceeds via undissociated neighboring carboxyl group participation as was proposed for other phthalamic acid derivatives. One of the main hydrolysis products is naphthylamine, which is a known carcinogenic agent. Nap is as reactive as phthalamic acid but is less reactive than phthalanilic acid. MMX calculations on phthalamic acid derivatives showed that phthalanilic acid has the closest distance for a most efficient intramolecular catalysis. Additives such as cyclodextrin or metal ion do not affect the kinetics of the reaction.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
