Kinetic study of the reactions of some 2-L-3-Y-5-nitrothiophenes with primary and secondary amines in benzene

Abstract

The kinetics of the reactions of some 2-L-3-Y-5-nitrothiophenes (L = Br, OC 6H 5, OC 6H 4NO 2- p YCONH 2, CO 2Me) with n-butylamine, benzylamine, pyrrolidine and piperidine in benzene at 293.15 K have been studied with the aim of obtaining and insight into the role played by the ortho-like substituent (Y) in determining the occurrence and the form of base catalysis. The results obtained have also allowed to gain important information about the interactions between the substituents, the thiophene ring and the reaction centre.