Abstract
AbstractElectrochemical oxidation of some catecholamines such as dopamine (1), L‐dopa (2), and methyldopa (3) has been studied in various pH values, using cyclic voltammetry. The results indicate participation of catecholamines (1–3) in intramolecular cyclization reaction to form the corresponding o‐quinone derivatives (1d–3d). In various pHs, based on ECE mechanism, the observed homogeneous rate constants (kobs) of cyclization reaction were estimated by comparing the experimental cyclic voltammetric responses with the digital‐simulated results. Also, the cyclization rate constants (kcyc) were calculated using microscopic acidic dissociation constant of ammonium groups. The significant differences in electrochemical behavior, kobs and kcyc, of L‐dopa (2) and methyldopa (3) with dopamine (1) are due to the effects of the side chain carboxyl group. © 2004 Wiley Periodicals, Inc. Int J Chem Kinet 37: 17–24, 2005
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
