Abstract
Treatment of racemic P-stereogenic tertiary phosphines with enantiomerically pure bis-phosphoryl and bis-thiophosphoryl disulfides under kinetic resolution conditions (2:1 ratio) afforded enantiomerically enriched tertiary phosphine oxides or phosphine sulfides with ee values up to 39%. In a similar way from racemic tert-butylphenylchlorophosphine, optically active tert-butylphenylphosphinoyl chloride with 50% ee was obtained. The same reaction performed under dynamic kinetic resolution conditions (1:1 ratio of reagents) in the presence of chloride ions gave phosphinoyl chloride with 70% ee.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callSimilar Papers
More From: Tetrahedron Letters
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
