Abstract

A theory of membrane transport previously developed by us (Makino et al. Biophys. Chem. 35 (1990) 85; 38 (1990) 231; 43 (1992) 89) taking into account both of membrane volume and partition kinetic is extended to the situation in which a membrane consists of two submembranes. Such division of the membrane explicitly takes into account solute diffusion within the membrane phase. Equations are proposed which determine the time course of solute concentrations in the respective phases. Interestingly, overshoot phenomena can be observed in both submembranes under some conditions. Criteria for overshoot are given.

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