Abstract

The antioxidant activity of 1-[(2S)-3-mercapto-2-methylpropionyl]-L-proline (capoten; INN: captopril) at various concentrations was studied in a model reaction of methyl linoleate oxidation (initiated with 2,2′-azobisisobutyronitrile) at 60 ± 0.2°C in chlorobenzene solution and in aqueous emulsion system in the presence of copper(II) cations (catalyst) and cetyltrimethylammonium bromide (emulsifier). Captopril exhibits high antioxidant activity in the aqueous emulsion medium, which provides grounds for a more extensive investigation into the pharmacological activity of this drug.

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