Abstract

Migration of cells mediates key life processes starting from the beginning of life, through development and adulthood (1). This essential process is a teleological culmination of a complex molecular circuitry that generates signals that propagate like waves to orchestrate cytoskeletal rearrangements necessary for cell motion. To set the stage for discussing the role of kinases, which are proteins that transfer phosphate moieties to bio-molecular substrates, and are putative “star” players in cell migration, let us attempt to create a simplistic mental sketch of this intricate molecular interplay.

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