Kimura’s Disease of the Parotid Region: Report of 2 Cases and Review of the Literature

Abstract

Kimura’s disease (KD) is an uncommon chronic inflammatory disorder of unknown etiology. Clinically, it presents as solitary or multiple subcutaneous nodules, predominantly in the head and neck region, typically in the preauricular region, forehead, and scalp. Other localizations such as lacrimo-orbital involvement and upper extremities have been reported. The soft tissue localization is often associated with regional lymphadenopathy and, occasionally, with enlargement of the major salivary gland. Sporadic cases in non-Asian peoples with KD have been previously reported, but there are no reports of patients from islands in the Southwest Indian Ocean. We report 2 cases of KD with hypereosinophilia in patients who are natives of Madagascar and Mauritius. Our report shows that KD should be considered even in non-Asian patients in the diagnosis of hypereosinophilia-associated disease with head and neck subcutaneous mass.