Abstract
Introduction Kimura's disease is a rare inflammatory disorder of unknown cause, commonly seen in young Asian males. Case Report. A 61-year-old male patient presented with a history of right tonsillar mass and cervical lymphadenopathy. The patient underwent hematological investigation and imaging followed by resection of tonsillar mass. Based on histopathological and subsequent immunohistochemistry reports, the case was diagnosed as Kimura's disease of the tonsil. Discussion. Kimura's disease commonly presents as painless subcutaneous masses in the head and neck region or cervical lymphadenopathy. Kimura's disease presenting as a tonsillar mass is a very rare condition. Patients usually have peripheral eosinophilia and elevated levels of serum IgE. The diagnosis is based on the clinical and histopathologic findings in a biopsy of the mass and/or lymph node along with elevated peripheral eosinophil and serum IgE level. Conclusion The clinical presentation of Kimura's disease is highly variable. Kimura's disease should be considered as a differential diagnosis in patients presenting with a tonsillar mass. A high index of suspicion along with histopathological examination helps in the early diagnosis and management. Surgical excision is the treatment of choice.
Highlights
Kimura’s disease is a rare inflammatory disorder of unknown cause, commonly seen in young Asian males
Kimura’s disease is a chronic inflammatory disease of unknown etiology [1]. is disease typically occurs in young Asian male patients in their second to fourth decades of life, rare cases in other races and ethnicities have been seen [2]. e exact prevalence of Kimura’s disease is not known
We report a rare case of Kimura’s disease presenting as a unilateral tonsillar enlargement in an elderly man in Nepal. e clinical presentation, diagnosis, and treatment options for this rare disease are discussed in this article
Summary
Kimura’s disease is a chronic inflammatory disease of unknown etiology [1]. is disease typically occurs in young Asian male patients in their second to fourth decades of life, rare cases in other races and ethnicities have been seen [2]. e exact prevalence of Kimura’s disease is not known. Is disease typically occurs in young Asian male patients in their second to fourth decades of life, rare cases in other races and ethnicities have been seen [2]. Around 200 cases have been reported worldwide till date [3]. Most of these cases are reported in East and Southeast Asia, with a small number of cases reported in Europe and the Middle East [4, 5]. Kimura’s disease of the tonsil is a very rare condition. We report a rare case of Kimura’s disease presenting as a unilateral tonsillar enlargement in an elderly man in Nepal. E clinical presentation, diagnosis, and treatment options for this rare disease are discussed in this article We report a rare case of Kimura’s disease presenting as a unilateral tonsillar enlargement in an elderly man in Nepal. e clinical presentation, diagnosis, and treatment options for this rare disease are discussed in this article
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