Abstract
A 32-year-old woman presented with a fever and cervical lymphadenopathies. The research for Mycobacterium tuberculosis was negative. Tuberculin skin test was positive. Laboratory investigations showed an elevated erythrocyte sedimentation rate and a normal white blood cell count. Bacteriological and viral investigations were negative. Quantiferon-Tb Gold test was indeterminate. Thraco-abdominal and pelvic computed tomography, FDG-PET and gallium scintigraphy revealed no abnormalities. Histological study of cervical lymph node biopsy found signs in favor of histiocytic necrotizing lymphadenitis. There were no epithelioid cell granulomas. A test tuberculosis treatment was refused by the patient. The evolution was marked by spontaneous clinical and biological resolution in fifty days. The negative Lowenstein-Jensen culture eliminated formally the tuberculosis. KFD was thus the most likely diagnosis.
Highlights
Kikuchi-Fujimoto disease (KFD) occurring often in young women, is a histiocytic necrotizing lymphadenitis corresponding to a benign entity
KFD should be considered in the feature of lymphadenopathies associated to fever and weight loss to avoid the prescription of inappropriate treatment
The aim of this study is to emphasize on the diagnosis difficulty in case of peripheral lymphadenopathies, and to insist that KFD should be considered in these figure cases
Summary
Kikuchi-Fujimoto disease (KFD) occurring often in young women, is a histiocytic necrotizing lymphadenitis corresponding to a benign entity. It manifests frequently as lymphadenopathy and fever. KFD should be considered in the feature of lymphadenopathies associated to fever and weight loss to avoid the prescription of inappropriate treatment. An autoimmune process, such as systemic lupus erythematosus, may occur, and a serious follow-up is compulsory. The aim of this study is to emphasize on the diagnosis difficulty in case of peripheral lymphadenopathies, and to insist that KFD should be considered in these figure cases
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
