Abstract
The effect of uninephrectomy (UNX) or sham-operation (SO) in pregnant rats at the 5th-7th day of gestation upon pup kidney development was studied. In newborns, kidney wet weight was low in pups of the SO and UNX groups, kidney/body weight was low in UNX only; collagen was highest in UNX. At 6 weeks, wet weight was least in UNX; dry weight was low and %H2O high in SO and UNX; collagen/dry weight was high in SO and UNX. Maternal surgery (SO or UNX) appears to impose a non specific development deficit upon pups, although kidney collagen growth is sustained; no specific renotropic activity was evident in pups of the UNX groups.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
