Abstract

Myopia represents a major socioeconomic burden with an increasing prevalence worldwide. Pathologic myopia refers to myopic patients with structural changes in the posterior pole including different patterns of chorioretinal atrophy, choroidal neovascularization (CNV) and vitreomacular tractional diseases. Multifocal choroiditis (MFC) is one of the most frequent noninfectious posterior uveitis, and epidemiologically typically affects young myopic females. Acute and chronic chorioretinal atrophic changes are the hallmark feature of MFC, with CNV developing in almost one third of cases. Thus, differentiation of inflammatory lesions due to MFC or neurodenegerative lesions due to pathologic myopic is key in order to establish a particular prognosis, follow-up schedule, and therapeutic approach. The aim of the present manuscript is to summarize and illustrate the main multimodal imaging features of these diseases.

Highlights

  • Myopia is a medical condition characterized by blurred distance vision because of images of distant objects focusing in front of the retina, what is mostly due to excessive elongation of the eye

  • Focusing on chorioretinal atrophic changes related to pathologic myopica we can divide them into fundus tessellation, diffuse chorioretinal atrophy, and patchy chorioretinal atrophy (PCA)

  • PCA may develop from lacquer cracks (Lc), within areas of advanced diffuse chorioretinal atrophy, and along the border of posterior staphyloma [6, 7]

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Summary

Frontiers in Medicine

Fundus Imaging Findings to Recognize Multifocal Choroiditis in Patients With Pathological Myopia. Myopia represents a major socioeconomic burden with an increasing prevalence worldwide. Pathologic myopia refers to myopic patients with structural changes in the posterior pole including different patterns of chorioretinal atrophy, choroidal neovascularization (CNV) and vitreomacular tractional diseases. Multifocal choroiditis (MFC) is one of the most frequent noninfectious posterior uveitis, and epidemiologically typically affects young myopic females. Acute and chronic chorioretinal atrophic changes are the hallmark feature of MFC, with CNV developing in almost one third of cases. Differentiation of inflammatory lesions due to MFC or neurodenegerative lesions due to pathologic myopic is key in order to establish a particular prognosis, follow-up schedule, and therapeutic approach. The aim of the present manuscript is to summarize and illustrate the main multimodal imaging features of these diseases

INTRODUCTION
CHORIORETINAL ATROPHIC CHANGES
INFLAMMATORY CHORIORETINAL CHANGES
CHOROIDAL NEOVASCULARIZATION
OVERLAP BETWEEN PATHOLOGIC MYOPIA AND MULTIFOCAL CHORODITIS
THERAPEUTIC APPROACH
CONCLUSION
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