Ketones of Four or Five Carbons

Abstract

AbstractA ketone is an organic compound containing a carbonyl group (CO) attached to two carbon atoms and can be represented by the general formulaimageSeveral billion pounds of ketones are produced annually for industrial use in the United States. Those with the highest production volumes include acetone, methyl ethyl ketone, methyl isobutyl ketone, cyclohexanone, 4‐hydroxy‐4‐methyl‐2‐pentanone, isophorone, mesityl oxide, and acetophenone. Common methods used to manufacture ketones include aliphatic hydrocarbon oxidation, alcohol dehydration with subsequent oxidation, dehydrogenation of phenol, alkyl aromatic hydrocarbon oxidation, and condensation reactions.Ketones are used because of their ease of production, low manufacturing cost, excellent solvent properties, and desirable physical properties such as low viscosity, moderate vapor pressure, low to moderate boiling points, high evaporation rates, and a wide range of miscibility with other liquids. The low‐molecular‐weight aliphatic ketones are miscible with water and organic solvents, whereas the high‐molecular‐weight aliphatic and aromatic ketones are generally immiscible with water. Most ketones are chemically stable. The exceptions are mesityl oxide, which can form peroxides, and methyl isopropenyl ketone, which polymerizes. Most ketones are generally of low flammability.Ketones are commonly used in industry as solvents, extractants, chemical intermediates, and, to a lesser extent, flavor and fragrance ingredients. Ketones have also been reported in the ambient air, in wastewater treatment plants, and in oil field brine discharges.