Abstract
Ketamine in subanesthetic doses became popular as a recreational drug for its strong, quickly achievable antidepressant effect and short-acting, well-tolerated psychotomimetic (hallucinogenic and dissociative) effect. Numerous cases of genitourinary system dysfunction associated with ketamine use have been reported. We describe a case of ketamine-use-related symptoms of genitourinary system dysfunction in a 23-year-old man who was found to have acute cystitis and a history of using ketamine. We also discuss the epidemiology, the clinical presentation, and some aspects of treatment of ketamine-associated urinary tract dysfunction. In patients with lower urinary tract symptoms of uropathy and a history of ketamine use, the possibility of ketamine-induced uropathy should be included in the differential diagnosis. Further studies are necessary to help delineate guidelines for both diagnosis and management of ketamine-induced lower urinary tract dysfunction.
Highlights
A23-year-old man with a history of ketamine use (1.5 grams daily for 8 days) presented to the emergency department with abdominal pain that continued for 2 days
The result of urine polymerase chain reaction (PCR) test was negative for Chlamydia trachomatis and Neisseria
▪ Ketamine-associated urinary tract dysfunction should be considered in the differential diagnosis in a patient with lower urinary tract symptoms and a history of ketamine use
Summary
▪ Ketamine-associated urinary tract dysfunction should be considered in the differential diagnosis in a patient with lower urinary tract symptoms and a history of ketamine use. ▪ Management of ketamine-associated urinary tract dysfunction requires a multidisciplinary approach. Contrast-enhanced computed tomography (CT) of the abdomen and the pelvis showed mild urinary bladder wall thickening with diffuse mucosal hyperenhancement (Figure) suggestive of acute cystitis
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