Abstract
A total of 12 one-piece keratoprostheses were implanted in 6 eyes of 6 different patients with bilateral blinding, severe corneal disease with no possibility for a successful corneal transplantation. The prosthesis and the surgical procedure used are described. The short-term results were good, with 4 of the 6 patients obtaining a substantial visual improvement. In the remaining 2 patients preexisting pathology in the posterior segment of the eye was strongly suspected. However, the long-term complication rate was high, the chief problems being tissue necrosis around the prosthesis with eventual prosthesis loss and the development of retroprosthetic membranes. Repeated replacements of keratoprostheses extruded or removed because of complications were possible with restoration of the vision obtained after the first implantation.
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