Abstract
home Acta Veterinaria Brno Journal of the University of Veterinary Sciences Brno, Czech Republic Search:
Highlights
Chemical injuries of the eye may produce extensive damage to the ocular surface
Preferably from the contralateral eye, is a currently available technique to re-estabilish a normal phenotype of corneal epithelium after severe chemical injuries
In this study we observed the therapeutic effectiveness of immediate keratoplasty combined with limbal autotransplantation (LAT) and transplantation of amniotic membrane (AM) in severe experimental alkali injury
Summary
Such injuries result in immediate damage to corneal and conjunctival epithelium, corneal stroma and limbus The latter is a carrier of corneal stem cells and is indispensable for the maintenance of a healthy corneal epithelial surface. Amniotic membrane transplantation in the acute stage is an additional procedure used to promote epithelial healing and to reduce inflammation, vascularization and scarring after alkali burns (Meller et al 2000). Even these two procedures done simultaneously may not prevent late corneal opacification. Immediate keratoplasty, combined with limbal autograft transplantation (LAT) and amniotic membrane transplantation, was investigated as a treatment for alkali chemical eye surface injury in rabbits. In this study we observed the therapeutic effectiveness of immediate keratoplasty combined with limbal autotransplantation (LAT) and transplantation of amniotic membrane (AM) in severe experimental alkali injury
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