Kayakalpam (Rejuvenative) herbs: An immunomodulators in Siddha system of medicine: A scientific review

Guru Prasad Chelliah Guru Prasad Chelliah,Carl Lewis John Carl Lewis John,Leo Praveen Chelliah Leo Praveen Chelliah

doi:10.30574/wjarr.2022.13.2.0167

Guru Prasad Chelliah Guru Prasad Chelliah, Carl Lewis John Carl Lewis John + Show 1 more

Open Access

https://doi.org/10.30574/wjarr.2022.13.2.0167

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Abstract

Background: Kayakalpam (Rejuvenative) medicine is one of the prime treatment technique in the Siddha system of medicine. Kayakalpam has potential to heal, rejuvenate and balance the vatham, pitham and kapam (tri-dhosas) which make the body and mind to attain its stability. Several studies have been done on Kayakalpam medicines, but, this review article states about few Kayakalpam herbs, their chemical constituents, pharmacological activities and its immuno-modulatory mechanism towards the prevention and management of non-communicable diseases and several other diseases. Methods: A literature review was conducted using the following scientific databases: PubMed, Research gate, Science Direct, Google scholar, Ayurvedic Pharmacopoeia of India and Siddha Pharmacopoeia of India. The aim was to identify published data on traditionally used medicinal plant for rejuvenation and immuno-modulatory effect. From that, few Kayakalpam herbs have been chosen which has been mentioned in the Siddha literature and reviewed its nature. Conclusion: This literature review reveals the potential effect of Kayakalpam herbs and its nature. Beyond any doubt it will help in prevention and management of non-communicable diseases and several other diseases.

Highlights

According to the World Health Organization (WHO), about three-quarters of the world population rely upon traditional remedies for the health care of its people
Rising burden of Non-Communicable Diseases (NCDs) is due to rapid urbanization and social development occurring in the country over the past two decades
Kayakalpam is one of the unique therapeutic formulations in Siddha system advocated for rejuvenation, longevity and elimination of disease causing factors

Summary

Methods

A literature review was conducted using the following scientific databases: PubMed, Research gate, Science Direct, Google scholar, Ayurvedic Pharmacopoeia of India and Siddha Pharmacopoeia of India. Few Kayakalpam herbs have been chosen which has been mentioned in the Siddha literature and reviewed its nature

Conclusion

Introduction

Material and methods

Brief history of Siddha System of Medicine (SSM)

KayaKalpam

Immuno-modulation by Medicinal Plants

Aloe barbadensis Mill

Asparagus racemosus Willd

Solanum trilobatum Linn

Tinospora cordifolia Willd

Findings