Abstract
Short-term culture of cells from a cystic adenoma of the ovary removed from a 66-year-old woman, revealed normal cells, cells with a supernumerary C chromosome, and cells with two apparently similar C chromosomes. This was interpreted as evidence of clonal evolution, firstly by acquisition of a supernumerary chromosome followed by its occasional duplication leading to a second clone with 48 chromosomes. The chromosomal finding and the histological appearance of the tumour agree in indicating that this case illustrates the cytogenetic basis for the beginning of an evolution towards malignancy.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.