Abstract
Skin strippings harvest the malignant melanoma cells eliminated through the stratum corneum. In this study, morphometry was applied to such non-invasive samplings in order to derive objective information about nuclear atypia. Cyanoacrylate skin surface strippings were collected from 140 malignant melanomas. Karyometry was performed to quantify the size and shape of malignant cell nuclei. Anisokaryosis was prominent although the outline of nuclei were rather smooth. Image analysis of skin strippings harvested from malignant melanomas shows that anisokaryosis is the major cytologic feature of malignant melanoma cells in transit in the stratum corneum.
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Schedule a callMore From: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
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