Abstract
To the Editor.— Kartagener's syndrome (chronic sinopulmonary symptoms and situs inversus) was shown to be a part of the immotile-cilia syndrome (chronic sinopulmonary symptoms and male sterility) when Afzelius and coworkers demonstrated that males with the immotile-cilia syndrome had immotile (or dysmotile) respiratory cilia and spermatozoa and that 50% of cases of the immotile-cilia syndrome had situs inversus. 1,2 The immotility is attributed to an ultrastructural defect of the respiratory cilium and sperm tail. 1 The inheritance is autosomal recessive. Absence of frontal sinuses is a recognized association. 2 This is to my knowledge the second report of a case of Kartagener's syndrome with normal spermatozoa. The patient had chronic sinopulmonary symptoms, situs inversus, and absent frontal sinuses, while his spermatozoa had normal motility, ultrastructure, and fertilizing capacity. Thus, the entity can be regarded as a new subgroup of the immotile-cilia syndrome. Report of a Case.— A bachelor, aged 26
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: JAMA: The Journal of the American Medical Association
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
