Abstract
ABSTRACTKaposi sarcoma is an angioproliferative disorder that ranges from a single indolent skin lesion to respiratory and gastrointestinal/visceral involvement. Kaposi sarcoma is rare in non-immunosuppressed patients. Nineteen cases of penile Kaposi sarcoma in HIV-negative patients were reported in 2012. We present the case report of a 48-year-old male patient with no previous medical history, who came to our urology clinic presenting a purple-color papule on the penis glans. Lab tests revealed negative serology for HIV, but tissue PCR was positive for human herpesvirus 8. Histopathology examination after lesion excision was compatible with Kaposi sarcoma. No other cutaneous or mucosal lesions were present. Primary Kaposi sarcoma of the penis is rare, but may occur in non-immunosuppressed patients.
Highlights
Kaposi sarcoma (KS) is an angioproliferative disorder that requires human herpesvirus 8 (HHV-8) infection, known as KS associated with herpesvirus (KSHV), for its development.[1,2] There are four clinical-epidemiological forms of KS: classic; endemic; iatrogenic; and HIV-associated.(3)einstein (São Paulo). 2019;17(1):1-3Aguilar Guevara JF, Lacarra Fernández S, Rojas Claros O, Giral Villalta P, Cebrián Lostal JL, Resano Abarzuza MA ❚❚CASE REPORTA 48-year-old male patient with no previous medical history presented to our urology clinic with a penile lesion of 1-month duration
Kaposi sarcoma is named after Moritz Kaposi, a Hungarian dermatologist and faculty member of the University of Vienna, who first described it in 1872 as an “idiopathic multiple pigmented sarcoma of the skin”.(4) The disease ranges from a single indolent skin lesion to extensive respiratory and gastrointestinal visceral involvement
Kaposi sarcoma is classified in four types based on its clinical characteristics: [1] classic, which has an indolent and rarely fatal course; [2] endemic, which may present an indolent or aggressive disease course; [3] iatrogenic, which is often reversed by adjusting immunosuppressive agent doses; and [4] AIDS-associated
Summary
José Francisco Aguilar Guevara, Seila Lacarra Fernández, Oliver Rojas Claros, Pedro Giral Villalta, José Luis Cebrián Lostal, Miguel Angel Resano Abarzuza. Nineteen cases of penile Kaposi sarcoma in HIV-negative patients were reported in 2012. O sarcoma de Kaposi primário de pênis é raro, mas pode ocorrer em pacientes não imunossuprimidos. ❚❚INTRODUCTION Kaposi sarcoma (KS) is an angioproliferative disorder that requires human herpesvirus 8 (HHV-8) infection, known as KS associated with herpesvirus (KSHV), for its development.[1,2] There are four clinical-epidemiological forms of KS: classic (predominantly located in the lower extremities of elderly men from Mediterranean areas); endemic (in young Africans with frequent local invasive and/or visceral involvement); iatrogenic (associated with immunosuppressive drug therapy, typically reported in renal allograft recipients); and HIV-associated (epidemic).(3). A 48-year-old male patient with no previous medical history presented to our urology clinic with a penile lesion of 1-month duration. Since the patient had not developed additional lesions, conservative treatment was chosen
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