Abstract

The incidence of HIV-related cancer before and during the ART era indicates that oncogenic viruses continue to contribute to the majority of these cancers and they are therefore considered opportunistic malignancies. ART has lead to a definitive decline in the incidence of certain AIDSdefining cancers including Kaposi sarcoma (KS) and nonHodgkin's lymphoma. Before ART, non-AIDS-related malignancies accounted for 1% of all causes of death in this population, this has now raised to over 25% because of the sharp decline of competitive risks, the relative frequent co-infection in this population with the oncogenic viruses Hepatitis B or C, the aging of the HIV-infected population and the possible direct contribution to oncogenesis by HIV-1 or ART.

Highlights

  • national Meeting of The Institute of Human Virology Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. [link 'here' using 'a href' to: http://www.biomedcentral.com/content/pdf/1742-4690-2-S1

  • ART has lead to a definitive decline in the incidence of certain AIDSdefining cancers including Kaposi sarcoma (KS) and nonHodgkin's lymphoma

  • Before ART, non-AIDS-related malignancies accounted for 1% of all causes of death in this population, this has raised to over 25% because of the sharp decline of competitive risks, the relative frequent co-infection in this population with the oncogenic viruses Hepatitis B or C, the aging of the HIV-infected population and the possible direct contribution to oncogenesis by HIV-1 or ART

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Summary

Introduction

Address: Wolfson Institute for Biomedical Research, UCL, London, UK Email: Chris Boshoff* - c.boshoff@ucl.ac.uk * Corresponding author ‡Presenting author from 2005 International Meeting of The Institute of Human Virology Baltimore, USA, 29 August – 2 September 2005 national Meeting of The Institute of Human Virology Meeting abstracts – A single PDF containing all abstracts in this Supplement is available here. The incidence of HIV-related cancer before and during the ART era indicates that oncogenic viruses continue to contribute to the majority of these cancers and they are considered opportunistic malignancies.

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