Abstract
Oxidative stress is an imbalance between the production of Reactive Oxygen Species (ROS) and antioxidants in the body. One plant that contains antioxidants is binahong leaves (Anredera cordifolia (Ten.) Steenis). To determine the compound content contained in binahong leaves, a total antioxidant capacity test and toxicity test were carried out on binahong leaves. This research used an in-vitro experimental study consisting of an antioxidant capacity test with DPPH (1.1-diphenyl-1-picrylhydrazil) and a bioassay, namely a toxicity test with the Brine Shrimp Lethality Test (BSLT) from binahong leaf extract. Extraction of binahong leaves is carried out using the maceration method using methanol solvent and then evaporated to obtain the extract. The total antioxidant capacity test was carried out using the Blois method, the Brine Shrimp Lethality Test (BSLT) toxicity test using the Meyer method. In the antioxidant capacity test, the IC50 value was 284.199 μg/mL, which means that the antioxidant capacity of binahong leaf extract is relatively low. In the toxicity test, the LC50 was obtained at 302.25 μg/mL, which means that binahong leaf extract has a level of toxicity against (Artemia salina L.) shrimp larvae. So it can be concluded that binahong leaf extract has relatively low antioxidant capacity and has toxic properties which are thought to have antimitotic properties.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.