Abstract
IntroductionJuvenile polyposis syndrome(JPS) is a rare autosomal dominant inherited condition. Hamartomatous polyps can affect the entire gastrointestinal tract but usually predominate in the colon. In this case report we present an unusual case of JPS that presented with massive gastric polyposis requiring a total gastrectomy.Case presentationA 51-year-old man presented with symptoms of gastric outlet obstruction and upper gastrointestinal bleeding. Gastroscopy showed massive gastric polyposis with a large antral polyp that had prolapsed through the pylorus causing gastric outlet obstruction. Initially endoscopic polypectomy was performed, but due to progressive symptoms a total gastrectomy was then performed. Histology confirmed massive gastric juvenile polyposis.ConclusionMassive gastric polyposis is an uncommon manifestation of juvenile polyposis syndrome. This case illustrates important principles in managing this condition.
Highlights
Juvenile polyposis syndrome(JPS) is a rare autosomal dominant inherited condition
Massive gastric polyposis is an uncommon manifestation of juvenile polyposis syndrome
We report an unusual case of massive gastric polyposis occurring in a patient with juvenile polyposis syndrome
Summary
Juvenile polyposis syndrome (JPS) is a rare autosomal dominant inherited condition These juvenile polyps can occur anywhere in the gastrointestinal tract but usually predominate in the colon. We report an unusual case of massive gastric polyposis occurring in a patient with juvenile polyposis syndrome. A 51-year-old man with known juvenile polyposis syndrome had been in a gastrointestinal polyposis screening program which had starting twenty years earlier when he was initially diagnosed with gastric and colonic juvenile polyps. Two years ago he required a laparotomy and small bowel resection for a large intussuscepting jejunal juvenile polyp causing obstruction. Genetic mutational analysis of the BMPR1A and SMAD4 genes was not performed
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
