Juvenile pleomorphic adenoma of the cheek: a case report and review of literature

Taufik Dalati,Mahmoud R Hussein

doi:10.1186/1746-1596-4-32

Taufik Dalati, Mahmoud R Hussein

Open Access

https://doi.org/10.1186/1746-1596-4-32

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Abstract

Pleomorphic adenoma, also called benign mixed tumor, is the most common tumor of the salivary glands. About 90% of these tumors occur in the parotid gland and 10% in the minor salivary glands. The most common sites of pleomorphic adenoma of the minor salivary glands are the palates followed by lips and cheeks. Other rare sites include the throat, floor of the mouth, tongue, tonsil, pharynx, retromolar area and nasal cavity. In children, intraoral pleomorphic adenomas of the cheek are extremely rare with only three cases reported to date. Here we report a case of pleomorphic adenoma of minor salivary glands of the cheek in a 17-year-old girl. The mass was removed by wide local excision with adequate margins, and after a follow-up period of three years there were no recurrences. To conclude, pleomorphic adenoma should be considered in the differential diagnosis of cheek masses in youngsters. Wide local excision is to be recommended as the treatment of choice. A close follow-up is necessary postoperatively.

Highlights

Pleomorphic adenomas are benign salivary gland tumors that represent about 3- 10% of the neoplasm of the head and neck region [1]
Pleomorphic adenoma consists of cells with epithelial and mesenchymal differentiation
The mucosa of the cheek is a uncommon site of occurrence for intraoral pleomorphic adenoma [10] and most of these cases have been reported in adults [11,12]

Summary

Introduction

Pleomorphic adenomas are benign salivary gland tumors that represent about 3- 10% of the neoplasm of the head and neck region [1]. Lee et al examined formalin-fixed, paraffin-embedded tissues from 13 pleomorphic adenomas of female patients. They used the polymerase chain reaction (HUMRA assay). A monoclonal pattern was seen in the stromal, epithelial elements in the majority of cases. These findings suggest that the (page number not for citation purposes). The mucosa of the cheek is a uncommon site of occurrence for intraoral pleomorphic adenoma [10] and most of these cases have been reported in adults [11,12]. The patient was followed up over a period of for 3 years and no recurrences were observed

Discussion

Conclusion

Findings

14. Cohen MA

20. Harada H