Abstract
The study of the cellular and molecular basis of the morphogenetic “status quo” action of juvenile hormone (Williams, 1961) has been hampered by the lack of a good system in which this action of juvenile hormone (JH) is completely separated from the events of cuticle synthesis itself. When we first found that there were two releases of ecdysone necessary for the larval-pupal transformation in the tobacco hornworm Manduca sexta (Truman and Riddiford, 1974) and that JH only affected the type of cuticle made if given before the first release (Truman et al., 1974), it seemed that these epidermal cells were ideal for a study of JH action. This paper will summarize our current state of knowledge about these cells and their response to hormones both in vivo and in vitro.
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