Abstract
Background: The Antisynthetase Syndrome (ASS) is a rare autoimmune disease considered as a subset of idiopathic inflammatory myopathies. This syndrome is associated with antisynthetase antibodies and clinical manifestations such as Raynaud’s phenomenon, mechanic’s hands and interstitial lung disease. Case presentation: Here in we reported a 16 years old Afghani girl who was diagnosed as having ASS. Rare diseases such as ASS should be suspected in idiopathic inflammatory myopathy patients who are resistant to standard medical regimens. Conclusion: In such cases, the use of Rituximab is strongly recommended. To the best of our knowledge is the first report of juvenile ASS in Middle East.
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