Justification of regional programs for the control and prevention of malignant neoplasms of the digestive system based on an international comparison of morbidity, mortality and survival rates (research based on materials from CI5 and Concord 3)

Abstract

In the Russian Federation, in comparison with the average European indicators, mortality with malignant neoplasm of the digestive system, even against the background of low morbidity, remains high. For the scientific substantiation and detailing of organizational measures to improve the control and prevention programs for malignant neoplasm of the digestive system, currently being carried out within the framework of the national project "Fight against cancer in 2019-2024", using the example of one of the typical regions of the Russian Federation - the Samara region, an international assessment was carried out the quality of medical care for this group of patients. At the same time, data on patients included in the database of the Samara population cancer registry in the period 2003-2017, data on cancer patients in the Samara region for the period 2008-2012, included in Cancer Incidence in Five Continents Vol.XI, as well as data on patients with malignant neoplasms registered in the Samara region in 2010-2014 and included in the Concord 3 study. The quality of medical care was assessed for all localizations of the digestive system based on the analysis of trends in morbidity, mortality and relative survival rates. An international study has shown that in the Samara region, in comparison with European countries, practically in all malignant neoplasms of the digestive system, with a low morbidity, high mortality and low survival are noted. Based on the data of a reliable onco-epidemiological study carried out in accordance with international standards, it was found that in the regions of the Russian Federation, when developing the financial, human and organizational resources of the national project to combat malignant neoplasms, special attention should be paid to primary prevention programs for colon cancer, liver cancer and gallbladder; organization of comprehensive colorectal cancer screening programs; as well as active implementation of programs for early diagnosis and effective treatment of stomach, pancreas, liver, esophagus and gallbladder cancer.