Abstract
Cancer is the second leading cause of mortality worldwide, responsible for one in six deaths. Conventional treatments have been advancing and becoming more effective, but scientists continue to seek alternative and complementary treatments. Nature is the main source of alternative medicine for various diseases, including cancer. For example, mineral-rich plants are widely available in Indonesia and have been used traditionally to treat illnesses. One of them is the bidara fruit (Ziziphus mauritiana), which has medicinal compounds such as flavonoid, phenolic and tannin. The 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) antioxidant assay test shows an IC50 234,2139 ppm and classifies bidara fruit extract as a medium antioxidant. Meanwhile, the Brine Shrimp Lethality Test (BSLT) test shows an LC50 4,5449 and classifies bidara fruit extract as having high toxicity.
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