JS-ISH-KSH-4: EPIDEMIOLOGY OF RESISTANT HYPERTENSION IN KOREA: ABPM REGISTRY DATA

Abstract

Resistant hypertension (RH) may be one of the major challenges in improving the control rate in hypertension (HTN) management. Accurate diagnosis is usually difficult only by measuring office blood pressure(OBP). For 1230 subjects taking one or more antihypertensive medication (AHM) enrolled in the Korean Ambulatory Blood Pressure Monitoring (Kor-ABP) registry, the prevalence of RH was calculated when RH was defined as uncontrolled BP by three AHM classes including diuretic or controlled BP by 4 or more classes. Prevalence of RH was 11.9 % (146/1230). By using nighttime BP criteria, there was significant difference in the prevalence of RH for OBP versus nighttime BP. Masked uncontrolled HTN was 16.9 % and white-coat uncontrolled HTN was 14.1 %. For nighttime BP control status, odd ratios for smoking (odds ratio(OR), 0.624), drinking (OR, 1.512), coronary artery disease (OR, 0.604), calcium antagonist (OR, 1.705), and loop diuretics (OR, 0.454) were all significant. The prevalence of RH by nighttime BP was significantly higher than using daytime BP criteria.