Abstract
Alzheimer's disease (AD) and Parkinson's disease (PD) have become more prevalent as populations have aged. The treatment of many neurodegenerative disorders has not yet reached a point where it is possible to modify the disease's progression. Midlife hypertension is a significant predictor of cognitive impairment and neurodegenerative brain diseases in later life. These findings emphasize the importance of preventing and controlling hypertension as a neurodegenerative disease risk factor. In neurodegenerative diseases, autonomic dysfunction, neuropsychiatric, and sleep problems can lead to blood pressure variability (BPV). The BPV itself can exacerbate the disease's course. In light of this, it is crucial to regulate BPV in order to halt the progression of the degenerative process.
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