Abstract

Abstract Accurate estimation of shape and motion variability of the heart has important clinical implications for heart disease diagnosis. In this paper, we describe a framework which performs simultaneous segmentation and motion analysis of the left ventricle from 3D cardiac images. The left ventricle is formulated as an anisotropic linear elastic body represented by a set tetrahedrons constructed from sampling nodes. The elastic measure, shape coherence measure, prior distributions of the myocardial tissues and temporal driven measure. The displacement field and the segmentation result are simultaneously solved at the equilibrium state between the internal energy and the external energy. The experiment with 3D canine MR images illustrated its abilities and benefits. *Supported by the National Program on Key Basic Research Project (2003CB716104), National Natural Science Foundation of China (Grant Nos.604063040 and 60021201)

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