Abstract
Objective To observe the application of Jinfeng Pills combined with femoston in the infertile patients with thin endometrium. Methods Total of 104 cases of infertility with thin endometrium after ovulation induction and insufficiency of the kidney-yang on the day of human chorionic gonadotropin (hCG) injection were randomly divided into control group (52 cases with oral clomiphene and femoston), and study group (52 cases, who were pretreated with oral Jinfeng Pills for one cycle, and then given clomiphene, femoston combined with Jinfeng Pills). The two groups were treated for three cycles. The endometrial thickness and type, blood flow, clinical pregnancy rate were compared between the two groups before and after the treatment, as well as between the pregnancy group and the non-pregnancy group on the day of ovulation. Results After treatment, endometrial thickness in both groups were significantly improved [(9.93±0.15) mm, (8.05±0.42) mm vs. (5.97±0.16) mm, (5.99±0.14) mm, P<0.01], and study group was superior to control group (P<0.01). Endometrium type and blood flow after treatment were significantly improved compared with those before treatment (P=0.01, P=0.04, P<0.01, P=0.04), and the endometrium blood flow in study group was superior to control group (P=0.03). After treatment, the endometrial thickness [(9.45±0.78) mm vs. (8.59±1.00) mm], type and blood flow in pregnancy group were significantly improved compared with non-pregnancy group (P<0.01, P=0.04, P=0.04). Study group was superior to control group in clinical pregnancy rate (57.69% vs. 40.62%, P=0.02). Conclusion The combination of Jinfeng Pills and femoston can effectively improve the endometrial thickness, type and blood flow of endometrium, and improve the clinical pregnancy rate in clomiphene-induced ovulation patients with thin endometrium and infertility due to indufficiency of the kidney-yang. Key words: Clomiphene; Infertility patients with insufficiency of kidney-yang; Thin endometrium; Jinfeng Pills; Femoston
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