Abstract

Paget’s disease (PD) is a chronic bone disease characterised by increased resorption followed by excessive bone formation resulting in bone pain and fractures. PD is most common in the elderly and many are initially asymptomatic but can develop severe complications as disease progresses. Serum alkaline phosphatase is an important biochemical marker which is elevated in these patients. A clinical lion like face and radiological “cotton wool appearance” and a “jigsaw puzzle” pattern on histopathological examination are the characteristic features of PD. Bisphosphonates are the most commonly used drug of choice for treatment of patients with Paget’s disease. We discuss a classic case of PD involving a 70 year old female in this case report.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.