Abstract
Introduction: Primary small intestinal malignancies are rare with an incidence of less than 5% of all gastrointestinal malignancies and are more common in the middle-aged and elderly population. They are comprised either an adenocarcinoma, neuroendocrine tumor, gastrointestinal stromal tumor (GIST), lymphoma, and/or sarcoma. Case Presentation: Here we exhibit the case of a 23-year-old who presented with progressive nausea, weight loss, abdominal pain, and iron deficiency anemia and was diagnosed with leiomyosarcoma of the jejunum. Conclusion: We distinguish a GIST from leiomyosarcoma based on radiographic, histologic, and epidemiologic evidence and review the significance of prompt, accurate diagnosis as related to treatment.
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