Abstract
Sickle cell anaemia (SCA) is a common haemoglobinopathy among people from the Middle East, the Afro-Caribbean region, the Mediterranean and East India. While osteomyelitis of the long bones is a well-documented complication of SCA, there are few documented cases of SCA patients presenting with jaw osteomyelitis. We report three SCA patients with chronic jaw osteomyelitis who presented to the Department of Oral Health, Sultan Qaboos University Hospital, Muscat, Oman, between 2009 and 2013. Two of the patients had osteomyelitis of the mandible and the third had osteomyelitis of the maxilla. In addition, a brief review of the literature is presented focusing on the clinical presentation, diagnosis and management of jaw osteomyelitis among patients with SCA.
Highlights
Sickle cell anaemia (SCA) is a common haemoglobinopathy among people from the Middle East, the Afro-Caribbean region, the Mediterranean and East India
While osteomyelitis of the long bones is a welldocumented complication of SCA, there are few documented cases of SCA patients presenting with jaw osteomyelitis
We report three SCA patients with chronic jaw osteomyelitis who presented to the Department of Oral Health, Sultan Qaboos University Hospital, Muscat, Oman, between 2009 and 2013
Summary
Abstract: Sickle cell anaemia (SCA) is a common haemoglobinopathy among people from the Middle East, the Afro-Caribbean region, the Mediterranean and East India. A 23-year-old man with SCA presented to the Department of Oral Health, Sultan Qaboos University Hospital (SQUH), Muscat, Oman, in 2009 with pus discharge from the site of a recently extracted lower left third molar. A 16-year-old male patient with known SCA presented as an outpatient to the Department of Oral Health at SQUH in 2013 with pus discharge of two months’ duration from the lower right posterior alveolus He reported having had a VOC episode two weeks prior to the start of his symptoms. A 25-year-old male patient with SCA was referred to the Department of Oral Health at SQUH in 2013 with severe pain and swelling involving the right posterior maxilla following his admission to a local hospital due to a severe VOC He had a history of frequent hospital admissions, bilateral avascular necrosis of the femoral heads and was currently receiving oral hydroxyurea.
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