Abstract
Question: A 28-year-old white man with diffuse large B-cell lymphoma developed sudden weight gain and jaundice 2 weeks after autologous stem cell transplantation. The patient complained about abdominal pain and fatigue. He had no prior history of chronic liver disease or cholecystolithiasis but had initially displayed hepatic manifestation of lymphoma. On examination, he presented with an extended abdomen, leg edema, jaundice, and signs of hepatic encephalopathy. Lab results showed beginning liver failure with abrupt rise of liver enzymes (glutamate-oxaloacetate transaminase 3617 U/L, glutamate-pyruvate transaminase 1283 U/I) and hyperbilirubinemia (bilirubin 96.7 μmol/L) as well as deranged coagulation (international normalized ratio 2.5).
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