Abstract
Abstract Some pharmacological and clinical studies suggest that Juzentaihoto (JTT), one of the Japanese botanical medicines, has the effects of anti-tumour and immunological restoration in patients. These are related with natural killer T (NKT) cell function and might be induced by interleukin (IL)-12 and IL-18. These are reported to be the key molecules of induction and activation of NKT cells. Long administration of JTT induced up-regulation of serum IL-18 levels of the treated patients. IL-12 was also expressed abundantly in the livers of JTT-treated mice. We indicate here that JTT, one of the Japanese botanical medicines, may be useful for treatment of patients with liver and gastrointestinal tumours without producing severe adverse effects.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.