Abstract
Plain Language SummaryLichen planopilaris (LPP) is a condition where the immune system attacks hair follicles, causing permanent hair loss. Doctors have tried different medications to control the hair loss, but with limited success. JAK inhibitors are drugs that can affect the immune system and are used to treat conditions like rheumatoid arthritis and alopecia areata. We wanted to find out if JAK inhibitors could help with LPP. We looked at research articles in medical databases and found 7 articles that talked about 35 patients. Although the information on treatment is limited to studies that looked back at past cases and individual reports, JAK inhibitors could be a new option for treatment, especially when other treatments have not worked. We need more studies with larger groups of people to get more evidence on how well JAK inhibitors work for LPP.
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