Abstract
Three-dimensional (3D) vertex model is one of successful to understand morphogenetic dynamics of multicellular tissue. In particular, a fundamental 3D vertex model to express cellular arrangement in tissue is suggested (H. Honda, J. Theol. Biol. 2004). To our knowledge, there is currently no alternative model in the 3D vertex ones to simulate the arrangement. However the effects of cell and tissue large deformations along with physical and geometrical inconsistencies impede expressing a natural vertex dynamics. In this study, we suggest a novel model in which an artificial drift of morphogenetic dynamics is attenuated, and in which the geometrical inconsistencies are removed.
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