Abstract
Polycystic ovary syndrome (PCOS) is a common endocrine disorder of women, which occurs in 5% to 13% in women of reproductive age. It is one of the major reason of infertility in women. Therefore, the prediction of clinical pregnancy in women with PCOS is more challenging. Our aim was to investigate the IVF/ICSI outcomes in PCOD patients. In the present retrospective study, total of 126 women in 133 fresh IVF cycles were involved, where 42 patient were PCOD and 84 patient were non-PCOD (other factor of infertility). All the patients’ medical data of age, duration of infertility, factor of infertility, AMH hormone level, number of total retrieved oocyte, matured (M2) oocytes, day 3 cleaved embryos and biochemical pregnancy rates were used for this study and data were statistically analyzed by Student T-Test. After statistical analysis, significantly higher AMH level, higher number of total oocyte, mature oocyte and day3 cleaved embryos were observed. The biochemical pregnancy rate was also found to be higher in PCOD patient but it was not statistically significantly. In the present study, number of oocytes and cleaved embryos were found to significantly higher in PCOD group but biochemical pregnancy was not significant.
Highlights
Polycystic ovary syndrome (PCOS) is a common endocrine disorder of women, which occurs in 5% to 13% 1,2 in women of reproductive age
The results showed that the study groups were comparable in terms of female age, duration of infertility, AMH level, retrieved oocyte, mature oocyte, fertilized good quality cleaved embryos, endometrium thickness and positive biochemical pregnancy rate (%) after 14 days of embryo transfer
The significance of embryos transferred cycles were compared by Z Score Calculator online available software 14 and found to be significantly less (
Summary
Polycystic ovary syndrome (PCOS) is a common endocrine disorder of women, which occurs in 5% to 13% 1,2 in women of reproductive age. The low FSH concentration combined with high LH probably shows a well-preserved ovarian reserve and is associated with high pregnancy rates in IVF/ICSI cycles.[5] Antral follicle count evaluates by ultrasonography and the AMH level considered a diagnostic or even prognostic marker of PCOS. Polycystic ovary syndrome (PCOS) is a common endocrine disorder of women, which occurs in 5% to 13% in women of reproductive age It is one of the major reason of infertility in women. All the patients’ medical data of age, duration of infertility, factor of infertility, AMH hormone level, number of total retrieved oocyte, matured (M2) oocytes, day 3 cleaved embryos and biochemical pregnancy rates were used for this study and data were statistically analyzed by Student T-Test. Conclusion: In the present study, number of oocytes and cleaved embryos were found to significantly higher in PCOD group but biochemical pregnancy was not significant
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