Abstract
To assess the clinical literature describing the use of ivermectin in cases of treatment-resistant scabies infestations. Clinical literature accessed through a MEDLINE search (1966-July 2001) and the Cochrane Database. A limited number of case reports and case series describes successful intervention with ivermectin use in patients who have failed prior therapy. Ivermectin may serve as a viable alternative therapy as the incidence of resistant scabitic infestations increases. Ivermectin appears to be a safe and effective alternative for patients with treatment-resistant scabies. Larger, controlled clinical trials are required before this therapy can be recommended in the general population or as primary therapy.
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