Abstract

In clinical practice ventricular assist devices are generally applied with a constant rotary speed. The lack of adaptivity to changes in hemodynamic conditions might result in underpumping or suction. In this paper, a norm-optimal iterative learning control algorithm incorporating variable cycle durations is developed and tested in silico to changes in afterload, contractility, and heart rate. To simulate exercise, a fourth experiment with parallel variations of preload, afterload, contractility and heart rate is done. For this purpose, a simplified simulation model of the cardiovascular system is used. The results confirm that the algorithm is able to prevent the dilatation of the ventricle and adapt to varying cycle lengths.

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