Abstract
Electric force is the most popular technique for bioparticle transportation and manipulation in microfluidic systems. In this paper, the iterative dipole moment (IDM) method was used to calculate the dielectrophoretic (DEP) forces of particle-particle interactions in a two-dimensional DC electric field, and the Lagrangian method was used to solve the transportation of particles. It was found that the DEP properties and whether the connection line between initial positions of particles perpendicular or parallel to the electric field greatly affect the chain patterns. In addition, the dependence of the DEP particle interaction upon the particle diameters, initial particle positions, and the DEP properties have been studied in detail. The conclusions are advantageous in elelctrokinetic microfluidic systems where it may be desirable to control, manipulate, and assemble bioparticles.
Highlights
Microfluidic systems are widely used for biochemical analysis over the past decade, and electric forces are often used as an efficient and effective transport mechanism, which does not involve the intervention of moving parts and offers good manipulation over sample handling
Deposition of bioparticles and colloids onto the surface [1] is very important for many biochemical processes, such as assembly of carbon nanotubes [2, 3] and trapping of nanoparticles and nanoparticle synthesis [4,5,6]
Maxwell stress tensor (MST) method [10] is complicated for the calculation of a large number of particles’ interaction [11]. e iterative dipole moment (IDM) [12–14] method, which does not solve complicated differential equations of an electric field while the particle is moving, was used in this work for calculating the DEP forces of particle interactions
Summary
Microfluidic systems are widely used for biochemical analysis over the past decade, and electric forces are often used as an efficient and effective transport mechanism, which does not involve the intervention of moving parts and offers good manipulation over sample handling. Equivalent dipole moment (EDM) has usually been used to calculate DEP force for single particle but cannot be used for the interaction between neighboring particles in an electric field.
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