It’s HLA-DR Not HLA-DQ Donor-specific Antibody That is Correlated to CAV After Heart Transplant

Abstract

Class II donor specific anti-HLA antibodies (DSA) have been correlated to subsequent CAV development. More specifically, HLA-DQ has been most reported for CAV development. Recently, HLA-DP has been added to the UNET computer. In this recent era, we are now able to compare class II antibodies to one another and assess outcome. We chose to evaluate our HTx patients who developed class II DSA in the first year after transplant.